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1st Incubation 16 - 18 hrs, 2nd incubation 2 hrs, 3rd incubation 30 min

Detection Target name
Human PYY

Target Synonyms
PYY, Peptide YY , Peptide Tyrosine Tyrosine, or Pancreatic Peptide YY3-36, Peptide YY (3-36), PYY-II, Peptide YY (1-36), PYY-I

Description
This enzyme immunoassay (EIA) kit is a stable and convenient assay system for human peptide YY (PYY). PYY was isolated initially by Tatemoto et al. (1980) from the extract of pig duodenum and shown to be a polypeptide consisting of 36 amino acids residues. PYY is homologous to pancreatic polypeptide (PP) and neuropeptide Y (NPY). PYY is localized mainly in endocrine cells in the intestine (ileum, colon, and rectum). PYY shows an inhibitory action on contraction of the gastrointestinal tract and on secretion of pancreatic and gastric juice. PYY is released by taking diet. The PYY level in human blood decreases after resection of the intestine, possibly be due to the decrease in number of the endocrine cells secreting PYY. The EIA kit is prepared by using synthetic human PYY (3-36) as standard and biotinylated human PYY (3-36) as labeled antigen. The kit can be used for measurement of PYY in human plasma or serum with high sensitivity. It will be a specifically useful tool for PYY research.

This product is useful for Diabetes / Obesity study.

Technical Information