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1st Incubation 1 hrs, 2nd incubation 30 min, 3rd incubation 30 min

Detection Target name
Human HAI-1

Target Synonyms
HAI-1, Hepatocyte growth factor activator inhibitor type1, Kunitz-type protease inhibitor 1, SPINT1

Description
HAI-1 (Hepatocyte growth factor activator inhibitor type1) is one of two types of Kunitz-type serine protease inhibitors that was detected as a inhibitory factor of hepatocyte growth factor activator (HGFA), the factor that converts hepatocyte growth factor/scatter factor (HGF) into the active form. It is said to act as a transmembrane protein having two Kunitz domains, and to inhibit HGFA also as a free form secreted from membrane. HAI-1 also targets various other serine proteases such as matriptase and hepsin. It has been detected in the placenta, kidney, pancreas, prostate, and small intestine, and also reported to express in the liver cancer. This kit is designed to measure the free form of Human HAI-1. This product is useful for Gastroenterology study.