Home » Products » Reagents / Proteins » 01-507 Pasteurella multocida toxin
- 01-507
- Pasteurella multocida toxin
| Format | 370 ug/ml in 50% glycerol 5mM Tris-HCl(pH7.5) 0.1M NaCl |
|---|---|
| Storage | -20℃ |
| Package | 50ug |
| Download (protocol) | protocol |
| Note | Species origin Pasteurella Molecule Name multocida toxin Type (General) peptide/protein Full Description Pasteurella multocida toxin Pasteurella (PMT ) is produced by a gram-negative bacillus, Pasteurella multocida. PMT activates the Gq and G12/13 depending signaling pathway, which are ) subunit of the GTP trimer bound protein of animal cells. It does not activate the G11 dependent pathway although it is similar to Gq. This toxin binds to unidentified receptor and then is introduced into the cells by endocytosis and starts to function then. Therefore it does not function on cells without the receptor or defective in the endocytosis pathway. This product is a recombinant expressed by plasmid cloning of E. coli tox A gene. Its molecular weight is 145 kDa (Fig.1) |
