Home » Products » Reagents / Proteins » 05-005 HIV-1 Gag p24
- 05-005
- HIV-1 Gag p24
| Format | 50% glycerol 20mM Tris-HCl (pH7.5) 50mM NaCl 10mM mercaptoethanol |
|---|---|
| Storage | -70℃ |
| Package | 20ug |
| Download (protocol) | protocol |
| Note | Species origin HIV-1, Human immunodeficiency virus type 1 Molecule Name HIV-1 Reverse transcriptase Type (General) peptide/protein Full Description HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1 and is processed by the digestion of its precursor Gag p55 by HIV-1 protease. This protein is indispensable to the reproduction of AIDS virus and constitutes an essential element in the virus particle construction (1). As this protein is detectable from the early stage of AIDS virus infection, it is used as a marker for observation of the development in the patient’s condition after treatment, as it indicates the amount of virus in the blood. The product is over-expressed as a recombinant protein in E. coli with a plasmid carrying the Gag p24 coding region of HIV-1 virus, subtype B (2), and highly purified by several steps of chromatography (3). Its molecular weight is 24 kD, same as that of p24 purified from AIDS virus particles (Fig 1). |
